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ALPHA SUBUNIT, G-PROTEIN
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DeCS
Descriptor
English
:
GTP-Binding Protein alpha Subunits
Descriptor
Spanish
:
Subunidades alfa de la Proteína de Unión al GTP
Descriptor
Portuguese
:
Subunidades alfa de Proteínas de Ligação ao GTP
Synonyms
English
:
G-Protein alpha Subunit
GTP-Binding Protein alpha Subunit
G Protein alpha Subunit
GTP Binding Protein alpha Subunit
GTP Binding Protein alpha Subunits
alpha Subunit, G-Protein
Tree Number:
D08.811.277.040.330.300.200.100
D12.644.360.375.100
D12.776.157.325.332.100
D12.776.476.375.100
D12.776.543.325.100
Definition
English
:
The GTPase-containing subunits of
heterotrimeric GTP-binding proteins
. When dissociated from the heterotrimeric complex these subunits interact with a variety of
second messenger systems
.
Hydrolysis
of GTP by the inherent GTPase activity of the subunit causes it to revert to its inactive (heterotrimeric) form. The
GTP-Binding protein alpha subunits
are grouped into families according to the type of action they have on
second messenger systems.
History Note
English
:
2004; use HETEROTRIMERIC GTP-BINDING PROTEINS 2001-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
38130
Unique Identifier:
D044385
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS